SYNTHESIS OF NEW THIOSULFONATE DERIVATIVES WITH QUINONE AND QUINOXALINE FRAGMENTS

Authors

  • K. Bolibrukh National University "Lviv Polytechnic"
  • N. Monka National University "Lviv Polytechnic"
  • S. Polovkovych National University "Lviv Polytechnic"
  • V. Lubenets National University "Lviv Polytechnic"
  • V. Novikov National University "Lviv Polytechnic"
  • O. Khoumeri Laboratoire de Pharmaco-Chimie Radicalaire
  • T. Terme Laboratoire de Pharmaco-Chimie Radicalaire
  • P. Vanelle Laboratoire de Pharmaco-Chimie Radicalaire
  • O. Solovyov Shupyk National Medical Academy of Postgraduate Education

DOI:

https://doi.org/10.5755/j01.ct.64.2.6019

Keywords:

thiosulfonates, binucleophile, quinone, quinoxaline, nucleophilic substitution

Abstract

The optimisation of reaction conditions for obtaining thiosulfonate derivatives was performed. S,N-binucleophiles (sodium salts of 4-amino- and 4-acetylaminobenzenethiosulfonic acids) were used. The parameters of the reaction for the synthesis of derivatives by a thiosulfonate fragment were determined. Thiosulfonate derivatives based on a number of quinones and quinoxalines were synthesized.

DOI: http://dx.doi.org/10.5755/j01.ct.64.2.6019

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Published

2013-12-23

Issue

Section

TECHNOLOGY OF ORGANIC MATERIALS